Starting from Michael Porter's statement, according to which the cluster, the simple concentration, pack or spatial, territorial agglomeration of SMEs, specialized in a field (service, product, knowledge) or interrelated areas, can generate sustainable competitive advantages in the market (including global) in this sector of specialization, in this article I will try to address the issue regarding to the implementation of regional cluster concept and of sustainable regional development in the “Apuseni Mountains” area, taking into account as nucleus the mining project from Roșia Montană (Romania), which could represent a real lever and a good example for stimulating the mining industry competitiveness, both at regional and also at national level. The idea of designing a regional cluster model, that has as “motor drive” the mining project from Roșia Montană, which otherwise should be like a point of ”concentric radiance” in the purpose of launching of new economic activities and of developing of new specialized firms, could contribute to the increase of employment and of competitiveness of the companies in the region and implicitly to the improvement of the life of communities in which the cluster will be implemented, bringing also significant benefits to the Romanian state, both directly, but also indirectly through the multiplier effect and thus providing an example of good practice for other initiators of regional clusters.